L3MBTL2

Lethal(3)malignant brain tumor-like 2 protein is a protein that in humans is encoded by the L3MBTL2 gene.^[5][6]

L3MBTL2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2W0T, 3CEY, 3F70
Identifiers
Aliases	L3MBTL2, H-l(3)mbt-l, L3MBT, L3MBTL2 polycomb repressive complex 1 subunit, polycomb repressive complex 1 subunit, L3MBTL histone methyl-lysine binding protein 2
External IDs	OMIM: 611865; MGI: 2443584; HomoloGene: 12882; GeneCards: L3MBTL2; OMA:L3MBTL2 - orthologs
Gene location (Human) Chr. Chromosome 22 (human)[1] Band 22q13.2 Start 41,205,282 bp[1] End 41,231,271 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 E1 Start 81,548,090 bp[2] End 81,572,516 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pancreatic ductal cell tibialis anterior muscle parotid gland nasal epithelium skin of arm mucosa of ileum cerebellar vermis external globus pallidus gingival epithelium right frontal lobe Top expressed in spermatocyte epiblast otolith organ hand utricle cumulus cell superior cervical ganglion tail of embryo primary oocyte seminiferous tubule More reference expression data BioGPS n/a
Gene ontology Molecular function histone binding zinc ion binding protein binding metal ion binding methylated histone binding Cellular component nucleus nucleoplasm Biological process regulation of transcription, DNA-templated transcription, DNA-templated negative regulation of G0 to G1 transition chromatin organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 83746 214669 Ensembl ENSG00000100395 ENSMUSG00000022394 UniProt Q969R5 P59178 RefSeq (mRNA) NM_001003689 NM_031488 NM_001289711 NM_001289712 NM_145993 RefSeq (protein) NP_113676 NP_001276640 NP_001276641 NP_666105 Location (UCSC) Chr 22: 41.21 – 41.23 Mb Chr 15: 81.55 – 81.57 Mb PubMed search [3] [4]
Wikidata
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