LAS1L

LAS1-like protein is a protein that in humans is encoded by the LAS1L gene.^[5][6]

LAS1L
Identifiers
Aliases	LAS1L, Las1-like, dJ475B7.2, LAS1-like, ribosome biogenesis factor, LAS1 like, ribosome biogenesis factor, WTS, Las1, LAS1 like ribosome biogenesis factor, MRXSWTS
External IDs	OMIM: 300964; MGI: 1923380; HomoloGene: 32746; GeneCards: LAS1L; OMA:LAS1L - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xq12 Start 65,438,549 bp[1] End 65,534,810 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X|X C3 Start 94,978,941 bp[2] End 95,000,568 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right hemisphere of cerebellum right frontal lobe C1 segment sural nerve right testis left testis putamen cingulate gyrus Amygdala nucleus accumbens Top expressed in neural layer of retina primitive streak epiblast muscle of thigh supraoptic nucleus yolk sac tail of embryo superior frontal gyrus vas deferens transitional epithelium of urinary bladder More reference expression data BioGPS More reference expression data
Gene ontology Molecular function RNA binding endonuclease activity Cellular component MLL1 complex nucleolus membrane nucleus nucleoplasm cytoplasm preribosome, large subunit precursor Las1 complex Biological process rRNA processing maturation of 5.8S rRNA maturation of LSU-rRNA endonucleolytic cleavage involved in rRNA processing chromatin organization nucleic acid phosphodiester bond hydrolysis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 81887 76130 Ensembl ENSG00000001497 ENSMUSG00000057421 UniProt Q9Y4W2 A2BE28 RefSeq (mRNA) NM_001170649 NM_001170650 NM_031206 NM_001375328 NM_001375329 NM_001375330 NM_001375331 NM_001375332 NM_001375333 NM_001375334 NM_001375335 NM_001375336 NM_001375337 NM_152822 NM_001374717 RefSeq (protein) NP_001164120 NP_001164121 NP_112483 NP_001362257 NP_001362258 NP_001362259 NP_001362260 NP_001362261 NP_001362262 NP_001362263 NP_001362264 NP_001362265 NP_001362266 NP_690035 NP_001361646 Location (UCSC) Chr X: 65.44 – 65.53 Mb Chr X: 94.98 – 95 Mb PubMed search [3] [4]
Wikidata
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