LPAR5

Lysophosphatidic acid receptor 5 also known as LPA₅ is a protein that in humans is encoded by the LPAR5 gene.^{[5][6][7][8][9]} LPA₅ is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).^[10]

LPAR5
Identifiers
Aliases	LPAR5, GPR92, GPR93, KPG_010, LPA5, lysophosphatidic acid receptor 5
External IDs	OMIM: 606926; MGI: 2685918; HomoloGene: 10696; GeneCards: LPAR5; OMA:LPAR5 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12p13.31 Start 6,618,835 bp[1] End 6,635,960 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 F2 Start 125,044,883 bp[2] End 125,059,435 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gingival epithelium mucosa of ileum oral cavity mucosa of colon mucosa of sigmoid colon mucosa of transverse colon palpebral conjunctiva jejunal mucosa amniotic fluid endothelial cell Top expressed in jejunum colon esophagus ileum duodenum lip embryo embryo spleen stomach More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity molecular function Cellular component integral component of membrane plasma membrane membrane cellular component Biological process signal transduction G protein-coupled receptor signaling pathway biological process positive regulation of CREB transcription factor activity behavioral response to pain Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 57121 381810 Ensembl ENSG00000184574 ENSMUSG00000067714 UniProt Q9H1C0 Q149R9 RefSeq (mRNA) NM_020400 NM_001142961 NM_001163268 NM_001163269 RefSeq (protein) NP_001136433 NP_065133 NP_001156740 NP_001156741 Location (UCSC) Chr 12: 6.62 – 6.64 Mb Chr 6: 125.04 – 125.06 Mb PubMed search [3] [4]
Wikidata
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See also

• Lysophospholipid receptor