LRIG1

Leucine-rich repeats and immunoglobulin-like domains protein 1 is a protein that in humans is encoded by the LRIG1 gene.^[5][6][7] It encodes a transmembrane protein that has been shown to interact with receptor tyrosine kinases of the EGFR family^[8] and with MET^[9] and RET.^[10]

LRIG1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4U7L, 4U7M
Identifiers
Aliases	LRIG1, LIG-1, LIG1, leucine-rich repeats and immunoglobulin like domains 1, leucine rich repeats and immunoglobulin like domains 1
External IDs	OMIM: 608868; MGI: 107935; HomoloGene: 7380; GeneCards: LRIG1; OMA:LRIG1 - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p14.1 Start 66,378,797 bp[1] End 66,501,263 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6 D2|6 43.15 cM Start 94,581,510 bp[2] End 94,677,139 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte bronchial epithelial cell ventricular zone body of pancreas cardia gastric mucosa muscle layer of sigmoid colon pylorus internal globus pallidus lactiferous duct Top expressed in muscle of thigh lip ventricular zone dentate gyrus of hippocampal formation granule cell cerebellar cortex zygote secondary oocyte superior frontal gyrus tail of embryo esophagus More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 26018 16206 Ensembl ENSG00000144749 ENSMUSG00000030029 UniProt Q96JA1 P70193 RefSeq (mRNA) NM_015541 NM_008377 NM_001355269 RefSeq (protein) NP_056356 NP_001364273 NP_001364274 NP_001364275 NP_001364276 NP_001364277 NP_001364278 NP_032403 NP_001342198 Location (UCSC) Chr 3: 66.38 – 66.5 Mb Chr 6: 94.58 – 94.68 Mb PubMed search [3] [4]
Wikidata
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