LRRC3B

LRRC3B is a gene frequently epigenetically inactivated in several epithelial malignancies and inhibits cell growth and replication. Data suggest that the LRRC3B gene could be involved in the process of carcinogenesis as a tumor suppressor gene.^[5]

LRRC3B
Identifiers
Aliases	LRRC3B, LRP15, leucine rich repeat containing 3B
External IDs	MGI: 2384996; HomoloGene: 14190; GeneCards: LRRC3B; OMA:LRRC3B - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p24.1 Start 26,622,806 bp[1] End 26,717,537 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14|14 A1 Start 7,030,776 bp[2] End 7,112,248 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ventricular zone ganglionic eminence secondary oocyte Cerebellum cerebellar cortex cerebellar hemisphere right hemisphere of cerebellum Amygdala pars reticulata pars compacta Top expressed in habenula right ventricle cardiac muscles olfactory epithelium lobe of cerebellum interventricular septum ventral tegmental area cerebellar vermis extraocular muscle myocardium of ventricle More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 116135 218763 Ensembl ENSG00000179796 ENSMUSG00000045201 UniProt Q96PB8 Q8VCH9 RefSeq (mRNA) NM_052953 NM_001317808 NM_001317809 NM_001317810 NM_001317811 NM_001395645 NM_001395646 NM_001395647 NM_146052 RefSeq (protein) NP_001304737 NP_001304738 NP_001304739 NP_001304740 NP_443185 NP_666164 Location (UCSC) Chr 3: 26.62 – 26.72 Mb Chr 14: 7.03 – 7.11 Mb PubMed search [3] [4]
Wikidata
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