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LRRN2

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

LRRN2
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Leucine-rich repeat neuronal protein 2 is a protein that in humans is encoded by the LRRN2 gene.[5][6]

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The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.[6]

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