Lecithinase C

Phospholipase C (EC 3.1.4.3, lipophosphodiesterase I, Clostridium welchii α-toxin, Clostridium oedematiens β- and γ-toxins, lipophosphodiesterase C, phosphatidase C, heat-labile hemolysin, α-toxin) is an enzyme with systematic name phosphatidylcholine cholinephosphohydrolase.^[1][2][3][4] This enzyme catalyses the following chemical reaction

a phosphatidylcholine + H₂O ${\displaystyle \rightleftharpoons }$ 1,2-diacyl-sn-glycerol + phosphocholine

Phospholipase C
Identifiers
EC no.	3.1.4.3
CAS no.	9001-86-9
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

The bacterial enzyme is a zinc protein. It also acts on sphingomyelin and phosphatidylinositol.