Leukotriene B4 receptor 1

Leukotriene B₄ receptor 1, also known as BLT1 or BLT1 receptor, is a protein that in humans is encoded by the LTB4R gene.^[5][6][7]

LTB4R
Identifiers
Aliases	LTB4R, BLT1, BLTR, CMKRL1, GPR16, LTB4R1, LTBR1, P2RY7, P2Y7, leukotriene B4 receptor
External IDs	OMIM: 601531; MGI: 1309472; HomoloGene: 22477; GeneCards: LTB4R; OMA:LTB4R - orthologs
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q12 Start 24,311,450 bp[1] End 24,318,036 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14 C3|14 28.19 cM Start 56,003,419 bp[2] End 56,005,951 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in skin of abdomen blood skin of leg monocyte granulocyte spleen vagina olfactory zone of nasal mucosa bone marrow minor salivary glands Top expressed in granulocyte tibiofemoral joint lip bone marrow skin of external ear jejunum embryo embryo blood esophagus More reference expression data BioGPS n/a
Gene ontology Molecular function nucleotide binding G protein-coupled peptide receptor activity G protein-coupled receptor activity leukotriene receptor activity signal transducer activity leukotriene B4 receptor activity galanin receptor activity Cellular component integral component of membrane membrane raft plasma membrane integral component of plasma membrane membrane Biological process G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway leukotriene signaling pathway muscle contraction neuropeptide signaling pathway immune response signal transduction inflammatory response Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 1241 16995 Ensembl ENSG00000213903 ENSG00000285456 ENSMUSG00000046908 UniProt Q15722 O88855 RefSeq (mRNA) NM_181657 NM_001143919 NM_008519 RefSeq (protein) NP_001137391 NP_858043 NP_032545 Location (UCSC) Chr 14: 24.31 – 24.32 Mb Chr 14: 56 – 56.01 Mb PubMed search [3] [4]
Wikidata
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See also

• Eicosanoid receptor
• Etalocib, an antagonist at the leukotriene B₄ receptor