MAGED2

Melanoma-associated antigen D2 is a protein that in humans is encoded by the MAGED2 gene.^[5]

MAGED2
Identifiers
Aliases	MAGED2, 11B6, BCG-1, BCG1, HCA10, MAGE-D2, MAGE family member D2, BARTS5
External IDs	OMIM: 300470; MGI: 1933391; HomoloGene: 12750; GeneCards: MAGED2; OMA:MAGED2 - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xp11.21 Start 54,807,599 bp[1] End 54,816,015 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X|X F3 Start 149,589,366 bp[2] End 149,597,341 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in anterior pituitary left ovary right ovary ganglionic eminence right uterine tube stromal cell of endometrium Descending thoracic aorta canal of the cervix popliteal artery tibial arteries Top expressed in neural tube placenta mesencephalon lens genital tubercle ovary tail of embryo adrenal gland yolk sac uterus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component membrane extracellular region nucleus nucleolus cytosol platelet alpha granule lumen Biological process platelet degranulation female pregnancy renal sodium ion absorption Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10916 80884 Ensembl ENSG00000102316 ENSMUSG00000025268 UniProt Q9UNF1 n/a RefSeq (mRNA) NM_201222 NM_014599 NM_177433 NM_001199246 NM_030700 NM_001358566 NM_001358567 NM_001358568 RefSeq (protein) NP_055414 NP_803182 NP_957516 NP_055414.2 NP_803182.1 NP_957516.1 n/a Location (UCSC) Chr X: 54.81 – 54.82 Mb Chr X: 149.59 – 149.6 Mb PubMed search [3] [4]
Wikidata
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This gene is a member of the MAGED gene family. While the MAGEA and MAGEB genes are silent in normal tissues with the exception of testis and placenta, the MAGED genes are expressed ubiquitously. The MAGED genes are clustered on chromosome Xp11. This gene is located in Xp11.2, a hot spot for X-linked mental retardation (XLMR). Multiple alternatively spliced transcript variants have been found for this gene, however, the full length nature of some variants has not been defined.^[5]