MAML2

Mastermind-like protein 2 is a protein that in humans is encoded by the MAML2 gene.^[3][4][5]

MAML2
Identifiers
Aliases	MAML2, MAM-3, MAM2, MAM3, MLL-mastermind like transcriptional coactivator 2
External IDs	OMIM: 607537; GeneCards: MAML2; OMA:MAML2 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q21 Start 95,976,598 bp[1] End 96,343,195 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of paranasal sinus cartilage tissue lactiferous duct skin of hip parietal pleura bronchial epithelial cell visceral pleura renal medulla mucosa of ileum synovial membrane n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transcription coactivator activity Cellular component nuclear speck nucleus nucleoplasm Biological process Notch signaling pathway transcription initiation from RNA polymerase II promoter regulation of transcription, DNA-templated transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription of Notch receptor target positive regulation of Notch signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84441 n/a Ensembl ENSG00000184384 n/a UniProt Q8IZL2 n/a RefSeq (mRNA) NM_032427 n/a RefSeq (protein) NP_115803 n/a Location (UCSC) Chr 11: 95.98 – 96.34 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

See also

Details on the activity of the N-terminal domain of Mastermind-like protein 2 may be found under MamL-1.