MAN1A2

Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB is an enzyme that in humans is encoded by the MAN1A2 gene.^[5][6]

MAN1A2
Identifiers
Aliases	MAN1A2, MAN1B, mannosidase alpha class 1A member 2
External IDs	OMIM: 604345; MGI: 104676; HomoloGene: 55982; GeneCards: MAN1A2; OMA:MAN1A2 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p12 Start 117,367,449 bp[1] End 117,528,872 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 F2.2 Start 100,469,524 bp[2] End 100,592,819 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in middle temporal gyrus endothelial cell Epithelium of choroid plexus Brodmann area 23 parietal pleura epithelium of nasopharynx visceral pleura placenta superficial temporal artery skin of thigh Top expressed in genital tubercle medial dorsal nucleus tail of embryo lateral geniculate nucleus medial geniculate nucleus molar spermatocyte anterior amygdaloid area spermatid lateral septal nucleus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function calcium ion binding hydrolase activity hydrolase activity, acting on glycosyl bonds metal ion binding mannosyl-oligosaccharide 1,2-alpha-mannosidase activity catalytic activity Cellular component Golgi apparatus extracellular exosome endoplasmic reticulum membrane integral component of membrane Golgi membrane Biological process protein glycosylation N-glycan processing lung alveolus development metabolism glycoprotein metabolic process Golgi apparatus mannose trimming respiratory gaseous exchange by respiratory system Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10905 17156 Ensembl ENSG00000198162 ENSMUSG00000008763 UniProt O60476 P39098 RefSeq (mRNA) NM_006699 NM_010763 RefSeq (protein) NP_006690 NP_034893 Location (UCSC) Chr 1: 117.37 – 117.53 Mb Chr 3: 100.47 – 100.59 Mb PubMed search [3] [4]
Wikidata
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