Top Qs
Timeline
Chat
Perspective

MAN2A1

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

MAN2A1
Remove ads

Alpha-mannosidase 2 is an enzyme that in humans is encoded by the MAN2A1 gene.[5][6][7]

Quick Facts Identifiers, Aliases ...
Remove ads

Function

This gene encodes a protein which is a member of family 38 of the glycosyl hydrolases. The protein is located in the Golgi apparatus and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-linked glycosylation) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus.[7]

Remove ads

References

Further reading

Loading related searches...

Wikiwand - on

Seamless Wikipedia browsing. On steroids.

Remove ads