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MAN2A1
Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia
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Alpha-mannosidase 2 is an enzyme that in humans is encoded by the MAN2A1 gene.[5][6][7]
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Function
This gene encodes a protein which is a member of family 38 of the glycosyl hydrolases. The protein is located in the Golgi apparatus and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-linked glycosylation) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus.[7]
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References
Further reading
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