MAN2B2

Epididymis-specific alpha-mannosidase is an enzyme that in humans is encoded by the MAN2B2 gene.^[5][6][7]

MAN2B2
Identifiers
Aliases	MAN2B2, mannosidase alpha class 2B member 2, EpMAN
External IDs	MGI: 1195262; HomoloGene: 7411; GeneCards: MAN2B2; OMA:MAN2B2 - orthologs
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4p16.1 Start 6,575,189 bp[1] End 6,623,362 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 B3 Start 36,964,265 bp[2] End 36,987,997 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tendon of biceps brachii stromal cell of endometrium Descending thoracic aorta right coronary artery ascending aorta decidua parotid gland synovial joint popliteal artery tibial arteries Top expressed in spermatocyte spermatid granulocyte epithelium of small intestine yolk sac stroma of bone marrow seminiferous tubule tail of embryo ileum primary visual cortex More reference expression data BioGPS More reference expression data
Gene ontology Molecular function catalytic activity hydrolase activity alpha-mannosidase activity metal ion binding hydrolase activity, acting on glycosyl bonds carbohydrate binding mannan endo-1,6-alpha-mannosidase activity Cellular component extracellular region extracellular exosome lysosomal lumen extracellular space vacuolar membrane Biological process metabolism mannose metabolic process protein deglycosylation oligosaccharide catabolic process carbohydrate metabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23324 17160 Ensembl ENSG00000013288 ENSMUSG00000029119 UniProt Q9Y2E5 O54782 RefSeq (mRNA) NM_001292038 NM_015274 NM_008550 RefSeq (protein) NP_001278967 NP_056089 NP_032576 Location (UCSC) Chr 4: 6.58 – 6.62 Mb Chr 5: 36.96 – 36.99 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Epididymis-specific alpha-mannosidase precursor

Mannosidase alpha class 2B member

core-specific lysosomal alpha-1,6-Mannosidase

epididymis-specific alpha-mannosidase

mannosidase, alpha, class 2B, member