MENTAL domain

The MENTAL or MLN64 NH₂-terminal domain is a membrane-spanning domain that is conserved in two late endosomal proteins in vertebrates, MLN64 and MENTHO.^[1] The domain is 170 amino acids long.

MENTAL domain
Identifiers
Symbol	MENTAL
Pfam	PF10457
InterPro	IPR019498
PROSITE	PS51439
Available protein structures: Pfam   structures / ECOD   PDB RCSB PDB; PDBe; PDBj PDBsum structure summary

Current data indicates that this domain allows for dimerization between MLN64 and MENTHO molecules and with themselves.^[2] The domain may also direct cholesterol transport.