MFAP2

Microfibrillar-associated protein 2 is a protein that in humans is encoded by the MFAP2 gene.^[5][6]

MFAP2
Identifiers
Aliases	MFAP2, MAGP, MAGP-1, MAGP1, microfibrillar associated protein 2, microfibril associated protein 2
External IDs	OMIM: 156790; MGI: 99559; HomoloGene: 1801; GeneCards: MFAP2; OMA:MFAP2 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p36.13 Start 16,974,502 bp[1] End 16,980,632 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 D3 Start 140,737,729 bp[2] End 140,743,295 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in stromal cell of endometrium ventricular zone gallbladder canal of the cervix right coronary artery ganglionic eminence placenta Descending thoracic aorta ascending aorta body of uterus Top expressed in efferent ductule dermis ventricular zone maxillary prominence external carotid artery internal carotid artery vestibular sensory epithelium hand mandibular prominence umbilical cord More reference expression data BioGPS More reference expression data
Gene ontology Molecular function extracellular matrix structural constituent Cellular component microfibril extracellular region collagen-containing extracellular matrix Biological process embryonic eye morphogenesis post-embryonic eye morphogenesis extracellular matrix organization positive regulation of cold-induced thermogenesis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 4237 17150 Ensembl ENSG00000117122 ENSMUSG00000060572 UniProt P55001 P55002 Q99PM0 RefSeq (mRNA) NM_001135247 NM_001135248 NM_002403 NM_017459 NM_001161799 NM_008546 NM_001369292 RefSeq (protein) NP_001128719 NP_001128720 NP_002394 NP_059453 NP_001155271 NP_032572 NP_001356221 Location (UCSC) Chr 1: 16.97 – 16.98 Mb Chr 4: 140.74 – 140.74 Mb PubMed search [3] [4]
Wikidata
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Microfibrillar-associated protein 2 is a major antigen of elastin-associated microfibrils and a candidate for involvement in the etiology of inherited connective tissue diseases. This gene encodes two transcripts with two alternatively spliced 5' untranslated exons. These two transcripts contain the same eight coding exons, and therefore, encode the same protein.^[6]