MINDY4

MINDY lysine 48 deubiquitinase 4, also known as MINDY4, is a human gene.^[5]

MINDY4
Identifiers
Aliases	MINDY4, C7orf67, FAM188B, family with sequence similarity 188 member B, MINDY lysine 48 deubiquitinase 4, AQP1, CHIP28, AQP-1
External IDs	MGI: 3583959; HomoloGene: 49991; GeneCards: MINDY4; OMA:MINDY4 - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7p14.3 Start 30,771,417 bp[1] End 30,892,387 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 B3 Start 55,180,368 bp[2] End 55,297,207 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right uterine tube testicle right coronary artery right ovary left coronary artery left ovary right lung upper lobe of left lung ascending aorta gonad Top expressed in molar spermatocyte spermatid seminiferous tubule primary oocyte right kidney proximal tubule ventricular zone lens decidua More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 84182 330323 Ensembl ENSG00000106125 ENSMUSG00000038022 UniProt Q4G0A6 Q3UQI9 RefSeq (mRNA) NM_032222 NM_001142781 NM_177883 RefSeq (protein) NP_115598 NP_001136253 NP_808551 Location (UCSC) Chr 7: 30.77 – 30.89 Mb Chr 6: 55.18 – 55.3 Mb PubMed search [3] [4]
Wikidata
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Predictions

The predicted molecular weight is 84,400 daltons and pI is 6.465. pTARGET predicts the cellular location to be in the golgi apparatus with 93.9% confidence.^[6]

Expression

Based on the human tissue Gene Expression Omnibus profile, C7orf67 shows a marked increase in expression in the teratospermia disease state.^[7]