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MINK1

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

MINK1
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Misshapen-like kinase 1 is an enzyme that in humans is encoded by the MINK1 gene.[5][6][7]

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Function

Misshapen-like kinase 1 is a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.[7]

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Interactions

MINK1 has been shown to interact with NCK1.[8]

References

Further reading

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