MOGAT3

Monoacylglycerol O-acyltransferase 3 is a protein that in humans is encoded by the MOGAT3 gene.^[3]

MOGAT3
Identifiers
Aliases	MOGAT3, DC7, DGAT2L7, MGAT3, DGAT2L2, monoacylglycerol O-acyltransferase 3
External IDs	OMIM: 610184; HomoloGene: 80517; GeneCards: MOGAT3; OMA:MOGAT3 - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q22.1 Start 101,195,007 bp[1] End 101,201,038 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of transverse colon mucosa of ileum rectum right lobe of liver duodenum testicle jejunal mucosa mucosa of sigmoid colon appendix epithelium of colon n/a More reference expression data BioGPS n/a
Gene ontology Molecular function acyltransferase activity acyltransferase activity, transferring groups other than amino-acyl groups transferase activity diacylglycerol O-acyltransferase activity 2-acylglycerol O-acyltransferase activity Cellular component membrane integral component of membrane endoplasmic reticulum endoplasmic reticulum membrane Biological process lipid metabolism glycerol metabolic process triglyceride biosynthetic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 346606 n/a Ensembl ENSG00000106384 n/a UniProt Q86VF5 n/a RefSeq (mRNA) NM_001287147 NM_178176 n/a RefSeq (protein) NP_001274076 NP_835470 n/a Location (UCSC) Chr 7: 101.2 – 101.2 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Function

Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA.^[4]