MSTO1

Protein misato homolog 1 is a protein that in humans is encoded by the MSTO1 gene.^[5][6]

MSTO1
Identifiers
Aliases	MSTO1, MST, LST005, misato 1, mitochondrial distribution and morphology regulator, MMYAT, misato mitochondrial distribution and morphology regulator 1
External IDs	OMIM: 617619; MGI: 2385175; HomoloGene: 41228; GeneCards: MSTO1; OMA:MSTO1 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q22 Start 155,610,205 bp[1] End 155,614,951 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 F1 Start 88,812,414 bp[2] End 88,821,306 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in left testis right testis pituitary gland right ovary anterior pituitary left ovary tibial nerve right uterine tube body of uterus right lobe of thyroid gland Top expressed in spermatid yolk sac spermatocyte seminiferous tubule epiblast internal carotid artery embryo external carotid artery embryo primitive streak More reference expression data BioGPS n/a
Gene ontology Molecular function molecular function Cellular component mitochondrial outer membrane mitochondrion membrane cytoplasm Biological process mitochondrion organization mitochondrion distribution mitochondrial genome maintenance mitotic sister chromatid segregation mitotic spindle assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55154 229524 Ensembl ENSG00000125459 ENSMUSG00000068922 UniProt Q9BUK6 Q2YDW2 RefSeq (mRNA) NM_001256532 NM_001256533 NM_018116 NM_001350772 NM_001350773 NM_001350774 NM_001350775 NM_001350776 NM_001350777 NM_001350778 NM_001350779 NM_001350780 NM_001350781 NM_001350782 NM_001350783 NM_001350784 NM_001350785 NM_001350786 NM_001350787 NM_001350788 NM_001350789 NM_144898 RefSeq (protein) NP_001243461 NP_001243462 NP_060586 NP_001337701 NP_001337702 NP_001337703 NP_001337704 NP_001337705 NP_001337706 NP_001337707 NP_001337708 NP_001337709 NP_001337710 NP_001337711 NP_001337712 NP_001337713 NP_001337714 NP_001337715 NP_001337716 NP_001337717 NP_001337718 NP_659147 Location (UCSC) Chr 1: 155.61 – 155.61 Mb Chr 3: 88.81 – 88.82 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

The MSTO1 gene is 5134 base pairs (located in chromosome 1) and the MSTO1 protein is 570 aminoacids in length. It is located in the outer membrane of the mitochondrion, and is involved in the regulation of mitochondrial distribution and morphology.^[7]

Structure

The misato protein contains an N-terminal misato segment II myosin-like domain and a central tubulin domain.^[7]