MYADM

Myeloid-associated differentiation marker is a protein that in humans is encoded by the MYADM gene.^[5][6][7] It is the receptor by which human parechovirus enters cells.^[8]

MYADM
Identifiers
Aliases	MYADM, SB135, myeloid-associated differentiation marker, myeloid associated differentiation marker
External IDs	OMIM: 609959; MGI: 1355332; HomoloGene: 9668; GeneCards: MYADM; OMA:MYADM - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19q13.42 Start 53,864,763 bp[1] End 53,876,435 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7 A1|7 1.92 cM Start 3,337,605 bp[2] End 3,348,958 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in saphenous vein vena cava tail of epididymis synovial joint synovial membrane left uterine tube skin of hip decidua myometrium urethra Top expressed in internal carotid artery ascending aorta Ileal epithelium Paneth cell external carotid artery semi-lunar valve aortic valve carotid body endothelial cell of lymphatic vessel tunica media of zone of aorta More reference expression data BioGPS n/a
Gene ontology Molecular function molecular function Cellular component ruffle integral component of membrane membrane raft plasma membrane membrane cell-cell junction cortical actin cytoskeleton Biological process establishment of endothelial barrier negative regulation of protein phosphorylation negative regulation of protein kinase C signaling positive regulation of substrate adhesion-dependent cell spreading cell-cell junction maintenance membrane raft organization negative regulation of heterotypic cell-cell adhesion regulation of cell-substrate adhesion negative regulation of actin filament polymerization negative regulation of gene expression positive regulation of cell migration protein localization to plasma membrane Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 91663 50918 Ensembl ENSG00000179820 ENSMUSG00000068566 UniProt Q96S97 O35682 RefSeq (mRNA) NM_138373 NM_001020818 NM_001020819 NM_001020820 NM_001020821 NM_001290188 NM_001290189 NM_001290190 NM_001290191 NM_001290192 NM_001290193 NM_001290194 NM_001093764 NM_001093765 NM_001093766 NM_016969 RefSeq (protein) NP_001018654 NP_001018655 NP_001018656 NP_001018657 NP_001277117 NP_001277118 NP_001277119 NP_001277120 NP_001277121 NP_001277122 NP_001277123 NP_612382 NP_001087233 NP_001087234 NP_001087235 NP_058665 Location (UCSC) Chr 19: 53.86 – 53.88 Mb Chr 7: 3.34 – 3.35 Mb PubMed search [3] [4]
Wikidata
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