MYH13

Myosin-13 also known as myosin, heavy chain 13 is a protein which in humans is encoded by the MYH13 gene.^[5][6]

MYH13
Identifiers
Aliases	MYH13, MyHC-IIL, MyHC-eo, myosin, heavy chain 13, skeletal muscle, myosin heavy chain 13
External IDs	OMIM: 603487; MGI: 1339967; HomoloGene: 55780; GeneCards: MYH13; OMA:MYH13 - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17p13.1 Start 10,300,865 bp[1] End 10,373,130 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11 B3|11 40.85 cM Start 67,212,484 bp[2] End 67,262,412 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad skeletal muscle tissue tibialis anterior muscle muscle of thigh body of stomach synovial joint placenta gastrocnemius muscle fundus myometrium Top expressed in morula skeletal muscle tissue muscle of thigh quadriceps femoris muscle zone of skin blastocyst lung pancreas tail of embryo esophagus More reference expression data BioGPS n/a
Gene ontology Molecular function nucleotide binding actin binding microfilament motor activity cytoskeletal motor activity ATP binding calmodulin binding actin filament binding Cellular component cytoplasm myosin filament muscle myosin complex myofibril extracellular exosome myosin complex Biological process muscle contraction cellular response to starvation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8735 544791 Ensembl ENSG00000006788 ENSMUSG00000060180 UniProt Q9UKX3 n/a RefSeq (mRNA) NM_003802 NM_001081250 RefSeq (protein) NP_003793 n/a Location (UCSC) Chr 17: 10.3 – 10.37 Mb Chr 11: 67.21 – 67.26 Mb PubMed search [3] [4]
Wikidata
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Function

MYH13 is a myosin whose expression is restricted primarily to the extrinsic eye muscles which are specialized for function in eye movement.^[5]