MYH4

Myosin-4 also known as myosin, heavy chain 4 is a protein which in humans is encoded by the MYH4 gene.^[5]

MYH4
Identifiers
Aliases	MYH4, MYH2B, MyHC-2B, MyHC-IIb, myosin, heavy chain 4, skeletal muscle, myosin heavy chain 4
External IDs	OMIM: 160742; MGI: 1339713; HomoloGene: 123880; GeneCards: MYH4; OMA:MYH4 - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17p13.1 Start 10,443,290 bp[1] End 10,469,559 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11 B3|11 40.59 cM Start 67,128,855 bp[2] End 67,151,272 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Skeletal muscle tissue of rectus abdominis vastus lateralis muscle biceps brachii Skeletal muscle tissue of biceps brachii deltoid muscle muscle of thigh testicle thoracic diaphragm tibialis anterior muscle gastrocnemius muscle Top expressed in extensor digitorum longus muscle tibialis anterior muscle vastus lateralis muscle medial head of gastrocnemius muscle sternocleidomastoid muscle plantaris muscle triceps brachii muscle digastric muscle temporal muscle body of femur More reference expression data BioGPS n/a
Gene ontology Molecular function nucleotide binding actin binding microfilament motor activity double-stranded RNA binding ATPase activity cytoskeletal motor activity ATP binding calmodulin binding actin filament binding microtubule motor activity microtubule binding Cellular component cytoplasm myosin filament muscle myosin complex myofibril sarcomere myosin complex Biological process ATP metabolic process muscle contraction actin filament-based movement muscle filament sliding microtubule-based movement response to activity Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 4622 17884 Ensembl ENSG00000264424 ENSMUSG00000057003 UniProt Q9Y623 Q5SX39 RefSeq (mRNA) NM_017533 NM_010855 RefSeq (protein) NP_060003 NP_034985 Location (UCSC) Chr 17: 10.44 – 10.47 Mb Chr 11: 67.13 – 67.15 Mb PubMed search [3] [4]
Wikidata
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Function

MYH4 is a gene that encodes a sarcomeric myosin.