MYH8

Myosin-8 is a protein that in humans is encoded by the MYH8 gene.^[5][6]

MYH8
Identifiers
Aliases	MYH8, MyHC-peri, MyHC-pn, gtMHC-F, DA7, myosin, heavy chain 8, skeletal muscle, perinatal, myosin heavy chain 8
External IDs	OMIM: 160741; MGI: 1339712; HomoloGene: 68256; GeneCards: MYH8; OMA:MYH8 - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17p13.1 Start 10,390,322 bp[1] End 10,421,950 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11 B3|11 40.59 cM Start 67,167,950 bp[2] End 67,199,460 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in vastus lateralis muscle Skeletal muscle tissue of rectus abdominis triceps brachii muscle Skeletal muscle tissue of biceps brachii tibialis anterior muscle deltoid muscle glutes testicle kidney tubule gastrocnemius muscle Top expressed in masseter muscle esophagus fossa temporal muscle human fetus extraocular muscle internal carotid artery ankle joint muscle of thigh condyle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function myosin light chain binding nucleotide binding microfilament motor activity structural constituent of muscle ATPase activity cytoskeletal motor activity actin binding ATP binding calmodulin binding myosin phosphatase activity actin filament binding microtubule motor activity microtubule binding Cellular component cytoplasm myosin filament cytosol muscle myosin complex sarcomere myofibril myosin complex Biological process skeletal muscle contraction ATP metabolic process muscle contraction muscle filament sliding protein dephosphorylation microtubule-based movement Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 4626 17885 Ensembl ENSG00000133020 ENSMUSG00000055775 UniProt P13535 P13542 RefSeq (mRNA) NM_002472 NM_177369 RefSeq (protein) NP_002463 NP_796343 Location (UCSC) Chr 17: 10.39 – 10.42 Mb Chr 11: 67.17 – 67.2 Mb PubMed search [3] [4]
Wikidata
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Mutations in MYH8 are associated with Trismus pseudocamptodactyly syndrome.