MYL6B

Myosin light chain 6B is a protein that in humans is encoded by the MYL6B gene.^[5][6][7] Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain expressed in both slow-twitch skeletal muscle and in nonmuscle tissue.^[7]

MYL6B
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1OE9, 1W7I, 1W7J
Identifiers
Aliases	MYL6B, MLC1SA, myosin light chain 6B
External IDs	OMIM: 609930; MGI: 1917789; HomoloGene: 86887; GeneCards: MYL6B; OMA:MYL6B - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q13.2 Start 56,152,256 bp[1] End 56,159,647 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 D3 Start 128,330,026 bp[2] End 128,334,554 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in glutes Skeletal muscle tissue of biceps brachii muscle of thigh thoracic diaphragm ganglionic eminence tibialis anterior muscle epithelium of colon deltoid muscle left testis right testis Top expressed in thoracic diaphragm Hypothalamus genital tubercle white adipose tissue testicle ganglionic eminence tail of embryo synovial joint ankle joint muscle tissue More reference expression data BioGPS More reference expression data
Gene ontology Molecular function calcium ion binding structural constituent of muscle cytoskeletal motor activity protein binding Cellular component cytosol muscle myosin complex unconventional myosin complex extracellular exosome myosin complex Biological process muscle contraction skeletal muscle tissue development muscle filament sliding Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 140465 216459 Ensembl ENSG00000196465 ENSMUSG00000039824 UniProt P14649 Q8CI43 RefSeq (mRNA) NM_002475 NM_001199629 NM_172259 RefSeq (protein) NP_001186558 NP_002466 NP_758463 Location (UCSC) Chr 12: 56.15 – 56.16 Mb Chr 10: 128.33 – 128.33 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse