MYOZ1

Myozenin-1 is a protein that in humans is encoded by the MYOZ1 gene.^[5][6][7]

MYOZ1
Identifiers
Aliases	MYOZ1, CS-2, FATZ, MYOZ, myozenin 1
External IDs	OMIM: 605603; MGI: 1929471; HomoloGene: 23311; GeneCards: MYOZ1; OMA:MYOZ1 - orthologs
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q22.2 Start 73,631,612 bp[1] End 73,641,474 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14|14 A3 Start 20,699,175 bp[2] End 20,706,608 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in muscle of thigh Skeletal muscle tissue of rectus abdominis gastrocnemius muscle biceps brachii vastus lateralis muscle Skeletal muscle tissue of biceps brachii triceps brachii muscle glutes thoracic diaphragm deltoid muscle Top expressed in temporal muscle triceps brachii muscle muscle of thigh sternocleidomastoid muscle medial head of gastrocnemius muscle digastric muscle ankle quadriceps femoris muscle tibialis anterior muscle extensor digitorum longus muscle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function FATZ binding protein binding actin binding telethonin binding protein serine/threonine phosphatase inhibitor activity Cellular component cell projection nucleus pseudopodium actin cytoskeleton Z discdkac Biological process myofibril assembly negative regulation of transcription by RNA polymerase II skeletal muscle tissue development negative regulation of phosphoprotein phosphatase activity negative regulation of skeletal muscle tissue regeneration skeletal muscle fiber adaptation sarcomere organization negative regulation of calcineurin-NFAT signaling cascade Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 58529 59011 Ensembl ENSG00000177791 ENSMUSG00000068697 UniProt Q9NP98 Q9JK37 RefSeq (mRNA) NM_021245 NM_021508 RefSeq (protein) NP_067068 NP_067483 Location (UCSC) Chr 10: 73.63 – 73.64 Mb Chr 14: 20.7 – 20.71 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

MYOZ1 has been shown to interact with Telethonin,^[6][8] FLNC^[5][6][8] and Actinin, alpha 2.^[6]