MicroRNA 93

MicroRNA 93 is a functional RNA and a microRNA that in humans is encoded by the MIR93 gene. ^[3]

MIR93
Identifiers
Aliases	MIR93, MIRN9, MIRN93, hsa-mir-93, miR-93, microRNA 93
External IDs	OMIM: 612984; GeneCards: MIR93; OMA:MIR93 - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q22.1 Start 100,093,768 bp[1] End 100,093,847 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in bone marrow skeletal muscle tissue granulocyte endometrium gonad sural nerve blood rectum lymph node placenta n/a More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 407050 n/a Ensembl ENSG00000207757 n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) Chr 7: 100.09 – 100.09 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Function

The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70 nucleotide long stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target messenger RNAs (mRNA) through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.^[4]