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Mipafox

Chemical compound From Wikipedia, the free encyclopedia

Mipafox
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Mipafox is a highly toxic organophosphate insecticide that is an irreversible acetylcholinesterase inhibitor and is resistant to cholinesterase reactivators.[1] It was developed in the 1950s and is now believed to be no longer in use.[2]

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Toxicity

There are case reports of delayed neurotoxicity and paralysis due to acute exposure to mipafox.[3]

Synthesis

Phosphoryl chloride is first reacted with isopropylamine. The resulting product is then reacted with potassium fluoride or ammonium fluoride to produce mipafox.[4]

See also

References

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