Monocarboxylate transporter 10

Monocarboxylate transporter 10 (MCT 10), also known as aromatic amino acid transporter 1 and T-type amino acid transporter 1 (TAT1) and solute carrier family 16 member 10 (SLC16A10), is a protein that in humans is encoded by the SLC16A10 gene.^[5][6][7] SLC16A10 is a member of the solute carrier family.

SLC16A10
Identifiers
Aliases	SLC16A10, MCT10, PRO0813, TAT1, solute carrier family 16 member 10
External IDs	OMIM: 607550; MGI: 1919722; HomoloGene: 75089; GeneCards: SLC16A10; OMA:SLC16A10 - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6q21 Start 111,087,503 bp[1] End 111,231,194 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 B1 Start 39,909,528 bp[2] End 40,018,254 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gastrocnemius muscle secondary oocyte gonad Skeletal muscle tissue of rectus abdominis buccal mucosa cell Skeletal muscle tissue of biceps brachii duodenum vastus lateralis muscle jejunal mucosa vulva Top expressed in jejunum secondary oocyte islet of Langerhans epithelium of small intestine zygote liver blood primary oocyte ileum quadriceps femoris muscle More reference expression data BioGPS n/a
Gene ontology Molecular function aromatic amino acid transmembrane transporter activity thyroid hormone transmembrane transporter activity amino acid transmembrane transporter activity monocarboxylic acid transmembrane transporter activity Cellular component plasma membrane basolateral plasma membrane integral component of plasma membrane membrane integral component of membrane Biological process thyroid hormone transport amino acid transport aromatic amino acid transport transmembrane transport amino acid transmembrane transport monocarboxylic acid transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 117247 72472 Ensembl ENSG00000112394 ENSMUSG00000019838 UniProt Q8TF71 Q3U9N9 RefSeq (mRNA) NM_018593 NM_001114332 NM_028247 RefSeq (protein) NP_061063 NP_001107804 NP_082523 Location (UCSC) Chr 6: 111.09 – 111.23 Mb Chr 10: 39.91 – 40.02 Mb PubMed search [3] [4]
Wikidata
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Function

SLC16A10 mediates Na⁺-independent transport of tryptophan, tyrosine, phenylalanine, and L-DOPA.^[7]

See also

• Blue diaper syndrome