Myosin light chain 5

Myosin light chain 5 is a protein that, in humans, is encoded by the MYL5 gene. ^[3]

MYL5
Identifiers
Aliases	MYL5, myosin light chain 5, MYLC2
External IDs	OMIM: 160782; HomoloGene: 48110; GeneCards: MYL5; OMA:MYL5 - orthologs
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4p16.3 Start 673,580 bp[1] End 682,033 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of transverse colon skin of abdomen right adrenal cortex left adrenal cortex left testis right testis right hemisphere of cerebellum skin of leg apex of heart sural nerve n/a More reference expression data BioGPS n/a
Gene ontology Molecular function calcium ion binding structural constituent of muscle metal ion binding Cellular component cytosol muscle myosin complex myosin complex Biological process regulation of muscle contraction muscle contraction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 4636 n/a Ensembl ENSG00000215375 n/a UniProt Q02045 n/a RefSeq (mRNA) NM_002477 NM_001363650 n/a RefSeq (protein) NP_002468 NP_001350579 n/a Location (UCSC) Chr 4: 0.67 – 0.68 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Function

This gene encodes one of the myosin light chains, a component of the hexameric ATPase cellular motor protein myosin. Myosin is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene product, one of the regulatory light chains, is expressed in fetal muscle and in adult retina, cerebellum, and basal ganglia.