NCAPD2

Condensin complex subunit 1 also known as chromosome-associated protein D2 (CAP-D2) or non-SMC condensin I complex subunit D2 (NCAPD2) or XCAP-D2 homolog is a protein that in humans is encoded by the NCAPD2 gene.^[5][6][7] CAP-D2 is a subunit of condensin I, a large protein complex involved in chromosome condensation.

NCAPD2
Identifiers
Aliases	NCAPD2, CAP-D2, CNAP1, hCAP-D2, non-SMC condensin I complex subunit D2, MCPH21
External IDs	OMIM: 615638; MGI: 1915548; HomoloGene: 6497; GeneCards: NCAPD2; OMA:NCAPD2 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12p13.31 Start 6,493,356 bp[1] End 6,531,955 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 F2- F3 Start 125,144,970 bp[2] End 125,168,664 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ventricular zone ganglionic eminence bone marrow cell stromal cell of endometrium granulocyte rectum epithelium of colon gonad Descending thoracic aorta gastric mucosa Top expressed in tail of embryo ventricular zone genital tubercle mandibular prominence yolk sac maxillary prominence thymus spermatocyte epiblast somite More reference expression data BioGPS More reference expression data
Gene ontology Molecular function histone binding chromatin binding protein binding Cellular component cytoplasm membrane chromosome nucleoplasm condensin complex nuclear chromosome condensed chromosome nucleus condensed chromosome, centromeric region cytosol Biological process mitotic chromosome condensation meiotic chromosome condensation cell division chromosome separation chromosome condensation cell cycle mitotic cell cycle Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9918 68298 Ensembl ENSG00000010292 ENSMUSG00000038252 UniProt Q15021 Q8K2Z4 RefSeq (mRNA) NM_014865 NM_146171 RefSeq (protein) NP_055680 NP_666283 Location (UCSC) Chr 12: 6.49 – 6.53 Mb Chr 6: 125.14 – 125.17 Mb PubMed search [3] [4]
Wikidata
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