NDFIP2

NEDD4 family-interacting protein 2 is a protein that in humans is encoded by the NDFIP2 gene.^[5][6][7]

NDFIP2
Identifiers
Aliases	NDFIP2, N4WBP5A, Nedd4 family interacting protein 2
External IDs	OMIM: 610041; MGI: 1923523; HomoloGene: 12636; GeneCards: NDFIP2; OMA:NDFIP2 - orthologs
Gene location (Human) Chr. Chromosome 13 (human)[1] Band 13q31.1 Start 79,481,124 bp[1] End 79,556,077 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14|14 E2.3 Start 105,496,008 bp[2] End 105,546,732 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte skin of arm sperm pancreatic epithelial cell Brodmann area 46 mucosa of ileum skin of thigh palpebral conjunctiva jejunal mucosa Pons Top expressed in habenula deep cerebellar nuclei medial vestibular nucleus olfactory tubercle submandibular gland ventral tegmental area pontine nuclei lateral geniculate nucleus left colon globus pallidus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function signal transducer activity protein binding WW domain binding Cellular component cytoplasm integral component of membrane endosome Golgi apparatus multivesicular body membrane intracellular membrane-bounded organelle membrane Golgi membrane endoplasmic reticulum mitochondrion perinuclear region of cytoplasm endosome membrane Biological process negative regulation of gene expression negative regulation of protein transport positive regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of protein ubiquitination negative regulation of transporter activity signal transduction vacuolar transport metal ion transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 54602 76273 Ensembl ENSG00000102471 ENSMUSG00000053253 UniProt Q9NV92 Q91ZP6 RefSeq (mRNA) NM_001161407 NM_019080 NM_001394685 NM_001190989 NM_029561 RefSeq (protein) NP_001154879 NP_061953 n/a Location (UCSC) Chr 13: 79.48 – 79.56 Mb Chr 14: 105.5 – 105.55 Mb PubMed search [3] [4]
Wikidata
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Interactions

NDFIP2 has been shown to interact with NEDD4.^[8]