NDST2

Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 is an enzyme that in humans is encoded by the NDST2 gene.^[5][6]

NDST2
Identifiers
Aliases	NDST2, HSST2, NST2, N-deacetylase/N-sulfotransferase 2, N-deacetylase and N-sulfotransferase 2, N-HSST 2
External IDs	OMIM: 603268; MGI: 97040; HomoloGene: 20803; GeneCards: NDST2; OMA:NDST2 - orthologs
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q22.2 Start 73,801,911 bp[1] End 73,811,798 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14|14 A3 Start 20,773,798 bp[2] End 20,784,630 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in spleen granulocyte blood bone marrow tonsil right hemisphere of cerebellum gastric mucosa minor salivary glands sural nerve appendix Top expressed in neural layer of retina granulocyte dermis lip ankle joint ventricular zone yolk sac tail of embryo spermatocyte decidua More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transferase activity sulfotransferase activity catalytic activity hydrolase activity N-acetylglucosamine deacetylase activity [heparan sulfate-glucosamine N-sulfotransferase activity] deacetylase activity heparan sulfate sulfotransferase activity heparan sulfate N-acetylglucosaminyltransferase activity Cellular component integral component of membrane Golgi membrane Golgi apparatus membrane Biological process metabolism heparan sulfate proteoglycan biosynthetic process heparin biosynthetic process glycosaminoglycan biosynthetic process regulation of angiotensin levels in blood cellular process or phenomenon sulfur compound metabolic process heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8509 17423 Ensembl ENSG00000166507 ENSMUSG00000039308 UniProt P52849 P52850 RefSeq (mRNA) NM_001330107 NM_003635 NM_010811 RefSeq (protein) NP_001317036 NP_003626 NP_034941 Location (UCSC) Chr 10: 73.8 – 73.81 Mb Chr 14: 20.77 – 20.78 Mb PubMed search [3] [4]
Wikidata
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