NDUFC2

NADH dehydrogenase [ubiquinone] 1 subunit C2 is an enzyme that in humans is encoded by the NDUFC2 gene.^[5][6]

NDUFC2
Identifiers
Aliases	NDUFC2, B14.5b, CI-B14.5b, HLC-1, NADHDH2, NADH:ubiquinone oxidoreductase subunit C2, MC1DN36
External IDs	OMIM: 603845; MGI: 1344370; HomoloGene: 3344; GeneCards: NDUFC2; OMA:NDUFC2 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q14.1 Start 78,068,297 bp[1] End 78,079,862 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 E1 Start 97,049,210 bp[2] End 97,057,009 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right adrenal gland left adrenal cortex right adrenal cortex muscle of thigh mucosa of transverse colon olfactory zone of nasal mucosa buccal mucosa cell right lobe of thyroid gland left lobe of thyroid gland ganglionic eminence Top expressed in facial motor nucleus atrioventricular valve endocardial cushion medial ganglionic eminence anterior horn of spinal cord intercostal muscle digastric muscle brown adipose tissue lobe of cerebellum mammillary body More reference expression data BioGPS More reference expression data
Gene ontology Molecular function NADH dehydrogenase (ubiquinone) activity Cellular component cytoplasm integral component of membrane mitochondrial inner membrane mitochondrial respiratory chain complex I respirasome membrane mitochondrion plasma membrane azurophil granule membrane Biological process mitochondrial electron transport, NADH to ubiquinone neutrophil degranulation mitochondrial respiratory chain complex I assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 4718 68197 Ensembl ENSG00000151366 ENSMUSG00000030647 UniProt O95298 Q9CQ54 RefSeq (mRNA) NM_004549 NM_001204054 NM_001204055 NM_024220 RefSeq (protein) NP_001190983 NP_001190984 NP_004540 NP_077182 Location (UCSC) Chr 11: 78.07 – 78.08 Mb Chr 7: 97.05 – 97.06 Mb PubMed search [3] [4]
Wikidata
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The NDUF2 gene encodes one of the subunits of complex I, the first and largest complex of the mitochondrial respiratory chain.^[5]