NHLRC1

NHL repeat-containing protein 1 is a protein that in humans is encoded by the NHLRC1 gene.^[5][6]

NHLRC1
Identifiers
Aliases	NHLRC1, EPM2A, EPM2B, MALIN, bA204B7.2, NHL repeat containing E3 ubiquitin protein ligase 1
External IDs	OMIM: 608072; MGI: 2145264; HomoloGene: 18439; GeneCards: NHLRC1; OMA:NHLRC1 - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6p22.3 Start 18,120,440 bp[1] End 18,122,677 bp[1]
Gene location (Mouse) Chr. Chromosome 13 (mouse)[2] Band 13|13 A5 Start 47,166,033 bp[2] End 47,168,326 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in prefrontal cortex islet of Langerhans muscle of thigh right lobe of liver superior frontal gyrus stromal cell of endometrium gastrocnemius muscle Brodmann area 9 skin of leg right adrenal gland Top expressed in interventricular septum dorsomedial hypothalamic nucleus arcuate nucleus median eminence paraventricular nucleus of hypothalamus ventromedial nucleus ventral tegmental area suprachiasmatic nucleus habenula subiculum More reference expression data BioGPS More reference expression data
Gene ontology Molecular function metal ion binding protein binding ubiquitin protein ligase activity ubiquitin-protein transferase activity transferase activity Cellular component perinuclear region of cytoplasm cytosol endoplasmic reticulum nucleus Biological process autophagy protein polyubiquitination glycogen biosynthetic process positive regulation of protein ubiquitination protein ubiquitination proteasome-mediated ubiquitin-dependent protein catabolic process regulation of protein phosphorylation glycogen metabolic process regulation of gene expression regulation of protein ubiquitination response to endoplasmic reticulum stress cellular macromolecule metabolic process regulation of protein kinase activity regulation of protein localization to plasma membrane Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 378884 105193 Ensembl ENSG00000187566 ENSMUSG00000044231 UniProt Q6VVB1 Q8BR37 RefSeq (mRNA) NM_198586 NM_175340 RefSeq (protein) NP_940988 NP_780549 Location (UCSC) Chr 6: 18.12 – 18.12 Mb Chr 13: 47.17 – 47.17 Mb PubMed search [3] [4]
Wikidata
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See also

• NHL repeat