NOL5A

Nucleolar protein 56 is a protein that in humans is encoded by the NOP56 gene.^[5][6]

NOP56
Identifiers
Aliases	NOP56, NOL5A, SCA36, NOP56 ribonucleoprotein
External IDs	OMIM: 614154; MGI: 1914384; HomoloGene: 4660; GeneCards: NOP56; OMA:NOP56 - orthologs
Gene location (Human) Chr. Chromosome 20 (human)[1] Band 20p13 Start 2,652,593 bp[1] End 2,658,393 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 F1 Start 130,116,350 bp[2] End 130,121,233 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte right hemisphere of cerebellum body of pancreas right uterine tube right ovary left uterine tube left ovary lymph node anterior pituitary ventricular zone Top expressed in tail of embryo genital tubercle epiblast blastocyst ventricular zone embryo embryo neural tube thymus morula More reference expression data BioGPS More reference expression data
Gene ontology Molecular function histone methyltransferase binding protein binding snoRNA binding RNA binding cadherin binding Cellular component cytoplasm box C/D RNP complex sno(s)RNA-containing ribonucleoprotein complex small-subunit processome pre-snoRNP complex membrane nucleus nucleoplasm fibrillar center nucleolus Biological process rRNA processing rRNA modification ribosome biogenesis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10528 67134 Ensembl ENSG00000101361 ENSMUSG00000027405 UniProt O00567 Q9D6Z1 RefSeq (mRNA) NM_006392 NM_024193 RefSeq (protein) NP_006383 NP_077155 Location (UCSC) Chr 20: 2.65 – 2.66 Mb Chr 2: 130.12 – 130.12 Mb PubMed search [3] [4]
Wikidata
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Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them have not been determined.^[6]