NUMBL

Numb-like protein is a protein that in humans is encoded by the NUMBL gene.^[5][6][7]

NUMBL
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3F0W
Identifiers
Aliases	NUMBL, CAG3A, CTG3a, NBL, NUMB-R, NUMBLIKE, NUMBR, TNRC23, NUMB like, endocytic adaptor protein, NUMB like endocytic adaptor protein
External IDs	OMIM: 604018; MGI: 894702; HomoloGene: 68413; GeneCards: NUMBL; OMA:NUMBL - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19q13.2 Start 40,665,905 bp[1] End 40,690,972 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 A3 Start 26,957,858 bp[2] End 26,981,569 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pancreatic ductal cell buccal mucosa cell cardia trigeminal ganglion nipple trachea endothelial cell pylorus ventral tegmental area spinal ganglia Top expressed in dentate gyrus of hippocampal formation granule cell primary visual cortex superior frontal gyrus ventricular zone lip piriform cortex hippocampus proper ganglionic eminence cerebellar cortex subiculum More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component cytoplasm Biological process multicellular organism development positive regulation of neurogenesis neuroblast proliferation forebrain development protein metabolic process adherens junction organization neuroblast division in subventricular zone axonogenesis lateral ventricle development nervous system development cytokine-mediated signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9253 18223 Ensembl ENSG00000105245 ENSMUSG00000063160 UniProt Q9Y6R0 O08919 RefSeq (mRNA) NM_001289979 NM_001289980 NM_004756 NM_010950 RefSeq (protein) NP_001276908 NP_001276909 NP_004747 NP_035080 Location (UCSC) Chr 19: 40.67 – 40.69 Mb Chr 7: 26.96 – 26.98 Mb PubMed search [3] [4]
Wikidata
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Interactions

NUMBL has been shown to interact with MAP3K7IP2.^[8]