NXF2

Nuclear RNA export factor 2 is a protein that in humans is encoded by the NXF2 gene.^[5][6][7]

NXF2
Identifiers
Aliases	NXF2, CT39, TAPL-2, TCP11X2, nuclear RNA export factor 2
External IDs	OMIM: 300315; MGI: 1933192; HomoloGene: 88604; GeneCards: NXF2; OMA:NXF2 - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xq22.1 Start 102,247,167 bp[1] End 102,326,722 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X F1|X 56.31 cM Start 133,845,275 bp[2] End 133,865,503 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle gonad right testis left testis right uterine tube pituitary gland anterior pituitary olfactory zone of nasal mucosa hypothalamus islet of Langerhans Top expressed in spermatid Gonadal ridge embryo embryo testicle spermatocyte seminiferous tubule embryo ganglion of neuraxis genital tubercle More reference expression data BioGPS n/a
Gene ontology Molecular function nucleic acid binding RNA binding Cellular component cytoplasm nuclear RNA export factor complex nucleus nucleoplasm cytosol Biological process multicellular organism development poly(A)+ mRNA export from nucleus mRNA transport RNA transport mRNA export from nucleus Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 56001 83454 Ensembl ENSG00000269405 ENSMUSG00000009941 UniProt Q9GZY0 n/a RefSeq (mRNA) NM_022053 NM_001039910 NM_017809 NM_001289735 NM_001289736 NM_031259 RefSeq (protein) NP_071336 NP_001093156 n/a Location (UCSC) Chr X: 102.25 – 102.33 Mb Chr X: 133.85 – 133.87 Mb PubMed search [3] [4]
Wikidata
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Function

This gene is one of a family of nuclear RNA export factor genes. It encodes a protein that is involved in mRNA export, is located in the nucleoplasm, and is associated with the nuclear envelope. Alternative splicing seems to be a common mechanism in this gene family. Two variants have been found for this gene.^[7]

Interactions

NXF2 has been shown to interact with NUP214.^[5]