Nantenine

Nantenine
Clinical data
ATC code	none;
Identifiers
	IUPAC name (S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-benzo[de][1,3]benzodioxolo[5,6-g]quinoline;
CAS Number	2565-01-7 ;
PubChem CID	197001;
ChemSpider	170619 ;
UNII	XE0AU8C122;
ChEMBL	ChEMBL467094 ;
CompTox Dashboard (EPA)	DTXSID70180343 ;
Chemical and physical data
Formula	C20H21NO4
Molar mass	339.391 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CN1CCC2=CC(=C(C3=C2[C@@H]1CC4=CC5=C(C=C43)OCO5)OC)OC;
	InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1 ; Key:WSVWKHTVFGTTKJ-AWEZNQCLSA-N ;
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Nantenine is an alkaloid found in the plant Nandina domestica^[1] as well as some Corydalis species.^[2] It is an antagonist of both the α₁-adrenergic receptor^[3] and the serotonin 5-HT_2A receptor,^[4] and blocks both the behavioral and physiological effects of MDMA in animals.^[5]

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See also