Nucleolar phosphoprotein p130

Nucleolar phosphoprotein p130 is a protein that in humans is encoded by the NOLC1 gene.^[5][6][7]

NOLC1
Identifiers
Aliases	NOLC1, NOPP130, NOPP140, NS5ATP13, P130, Nucleolar phosphoprotein p130, nucleolar and coiled-body phosphoprotein 1, Srp40
External IDs	OMIM: 602394; MGI: 1918019; HomoloGene: 68818; GeneCards: NOLC1; OMA:NOLC1 - orthologs
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q24.32 Start 102,152,176 bp[1] End 102,163,871 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19|19 C3 Start 46,064,302 bp[2] End 46,073,969 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in middle temporal gyrus Brodmann area 23 germinal epithelium parietal pleura gingival epithelium epithelium of nasopharynx endothelial cell pancreatic epithelial cell visceral pleura sperm Top expressed in morula epiblast primitive streak tail of embryo somite embryo yolk sac embryo mandibular prominence maxillary prominence More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding GTP binding protein binding ATP binding RNA binding RNA polymerase I core binding protein heterodimerization activity DNA binding DNA-binding transcription factor activity transcription factor binding nuclear localization sequence binding protein domain specific binding box C/D RNA binding box H/ACA snoRNA binding box C/D snoRNP complex binding box H/ACA snoRNP complex binding Cellular component cytoplasm Cajal body nucleus nucleoplasm nucleolus fibrillar center box C/D RNP complex box H/ACA snoRNP complex Biological process rRNA processing cell cycle nucleolus organization regulation of translation neural crest formation neural crest cell development mitotic cell cycle response to osmotic stress positive regulation of cell population proliferation box H/ACA RNA metabolic process regulation of protein import into nucleus positive regulation of transcription, DNA-templated Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9221 70769 Ensembl ENSG00000166197 ENSMUSG00000015176 UniProt Q14978 E9Q5C9 RefSeq (mRNA) NM_001284388 NM_001284389 NM_004741 NM_001039351 NM_001039352 NM_001039353 NM_053086 RefSeq (protein) NP_001271317 NP_001271318 NP_004732 NP_001034440 NP_001034441 NP_001034442 NP_444316 Location (UCSC) Chr 10: 102.15 – 102.16 Mb Chr 19: 46.06 – 46.07 Mb PubMed search [3] [4]
Wikidata
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Interactions

Nucleolar phosphoprotein p130 has been shown to interact with coilin^[8] and CEBPB.^[9]