OGFOD1

2-oxoglutarate and iron-dependent oxygenase domain containing 1, also known as OGFOD1, is a human gene.^[5]

OGFOD1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4NHX, 4NHY
Identifiers
Aliases	OGFOD1, TPA1, 2-oxoglutarate and iron dependent oxygenase domain containing 1
External IDs	OMIM: 615857; MGI: 2442978; HomoloGene: 41238; GeneCards: OGFOD1; OMA:OGFOD1 - orthologs
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16q13 Start 56,451,521 bp[1] End 56,479,104 bp[1]
Gene location (Mouse) Chr. Chromosome 8 (mouse)[2] Band 8|8 C5 Start 94,763,826 bp[2] End 94,794,549 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in oocyte gastrocnemius muscle secondary oocyte biceps brachii muscle of thigh tibialis anterior muscle Skeletal muscle tissue of biceps brachii deltoid muscle gingival epithelium vastus lateralis muscle Top expressed in ventromedial nucleus central gray substance of midbrain paraventricular nucleus of hypothalamus lateral hypothalamus dentate gyrus of hippocampal formation granule cell superior colliculus ventral tegmental area Region I of hippocampus proper anterior amygdaloid area dorsomedial hypothalamic nucleus More reference expression data BioGPS n/a
Gene ontology Molecular function 2-oxoglutarate-dependent dioxygenase activity L-ascorbic acid binding iron ion binding oxidoreductase activity dioxygenase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen peptidyl-proline dioxygenase activity peptidyl-proline 3-dioxygenase activity metal ion binding Cellular component cytoplasmic stress granule nucleus cytoplasm cytosol Biological process regulation of translational termination cell population proliferation peptidyl-proline hydroxylation protein hydroxylation stress granule assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55239 270086 Ensembl ENSG00000087263 ENSMUSG00000033009 UniProt Q8N543 Q3U0K8 RefSeq (mRNA) NM_018233 NM_001324357 NM_001324358 NM_001324359 NM_001324360 NM_001324361 NM_001324362 NM_001324363 NM_001093757 NM_177767 RefSeq (protein) NP_001311286 NP_001311287 NP_001311288 NP_001311289 NP_001311290 NP_001311291 NP_001311292 NP_060703 NP_001087226 NP_808435 Location (UCSC) Chr 16: 56.45 – 56.48 Mb Chr 8: 94.76 – 94.79 Mb PubMed search [3] [4]
Wikidata
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