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ONECUT1

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

ONECUT1
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One cut homeobox 1 is a protein that in humans is encoded by the ONECUT1 gene. [5]

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Function

This gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple transcript variants.

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References

Further reading

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