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OPN1SW

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

OPN1SW
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Blue-sensitive opsin is a protein that in humans is encoded by the OPN1SW gene.[5][6][7] The OPN1SW gene provides instructions for making a protein that is essential for normal color vision. This protein is found in the retina, which is the light-sensitive tissue at the back of the eye.[8]

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The OPN1SW gene provides instructions for making an opsin pigment that is more sensitive to light in the blue/violet part of the visible spectrum (short-wavelength light). Cones with this pigment are called short-wavelength-sensitive or S cones.[8] In response to light, the photopigment triggers a series of chemical reactions within an S cone. These reactions ultimately alter the cell's electrical charge, generating a signal that is transmitted to the brain. The brain combines input from all three types of cones to produce normal color vision.[8]

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