OTOR

Otoraplin is a protein that in humans is encoded by the OTOR gene.^[5][6]

OTOR
Identifiers
Aliases	OTOR, FDP, MIAL1, otoraplin
External IDs	OMIM: 606067; MGI: 1888678; HomoloGene: 10600; GeneCards: OTOR; OMA:OTOR - orthologs
Gene location (Human) Chr. Chromosome 20 (human)[1] Band 20p12.1 Start 16,748,358 bp[1] End 16,770,062 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 G1 Start 142,920,393 bp[2] End 142,923,633 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in cochlea gonad Ventricular system of neuraxis embryo ventricular zone renal cortex ganglionic eminence mesencephalon liver gallbladder Top expressed in vestibular sensory epithelium utricle fossa intercostal muscle stria vascularis condyle vestibular membrane of cochlear duct trachea cochlea trigeminal ganglion More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 56914 57329 Ensembl ENSG00000125879 ENSMUSG00000027416 UniProt Q9NRC9 Q9JIE3 RefSeq (mRNA) NM_020157 NM_020595 RefSeq (protein) NP_064542 NP_065620 Location (UCSC) Chr 20: 16.75 – 16.77 Mb Chr 2: 142.92 – 142.92 Mb PubMed search [3] [4]
Wikidata
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The protein encoded by this gene is secreted via the Golgi apparatus and may function in cartilage development and maintenance. A frequent polymorphism in the translation start codon of this gene can abolish translation and may be associated with forms of deafness. This gene is a member of the melanoma-inhibiting activity gene family. In addition, alternate polyA sites exist for this gene.^[6]