PARD3B

Partitioning defective 3 homolog B is a protein that in humans is encoded by the PARD3B gene.^[5][6][7]

PARD3B
Identifiers
Aliases	PARD3B, ALS2CR19, PAR3B, PAR3L, PAR3LC, PAR3beta, Par3Lb, par-3 family cell polarity regulator beta
External IDs	MGI: 1919301; HomoloGene: 35389; GeneCards: PARD3B; OMA:PARD3B - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q33.3 Start 204,545,475 bp[1] End 205,620,162 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 C2 Start 61,677,983 bp[2] End 62,681,443 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve ventricular zone Achilles tendon epithelium of colon saphenous vein tibial arteries mucosa of ileum testicle gonad skin of hip Top expressed in Rostral migratory stream crypt of lieberkuhn of small intestine internal carotid artery external carotid artery sciatic nerve lumbar spinal ganglion renal corpuscle ciliary body iris intestinal villus More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding phosphatidylinositol binding Cellular component membrane endomembrane system bicellular tight junction cell junction nucleoplasm nuclear body protein-containing complex cytoplasm adherens junction cell cortex apical plasma membrane apical junction complex Biological process cell division cell cycle microtubule cytoskeleton organization cell adhesion protein localization establishment of cell polarity establishment or maintenance of epithelial cell apical/basal polarity establishment of centrosome localization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 117583 72823 Ensembl ENSG00000116117 ENSMUSG00000052062 UniProt Q8TEW8 Q9CSB4 RefSeq (mRNA) NM_001302769 NM_057177 NM_152526 NM_205863 NM_001081050 RefSeq (protein) NP_001289698 NP_476518 NP_689739 NP_995585 NP_001074519 Location (UCSC) Chr 2: 204.55 – 205.62 Mb Chr 1: 61.68 – 62.68 Mb PubMed search [3] [4]
Wikidata
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Interactions

PARD3B has been shown to interact with Mothers against decapentaplegic homolog 3.^[8]