PARP16

Poly (ADP-ribose) polymerase family, member 16 is a protein in humans that is encoded by the PARP16 gene. ^[5]

PARP16
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4F0D
Identifiers
Aliases	PARP16, ARTD15, C15orf30, pART15, poly(ADP-ribose) polymerase family member 16
External IDs	MGI: 2446133; HomoloGene: 9878; GeneCards: PARP16; OMA:PARP16 - orthologs
Gene location (Human) Chr. Chromosome 15 (human)[1] Band 15q22.31 Start 65,234,460 bp[1] End 65,300,618 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 C Start 65,102,635 bp[2] End 65,146,506 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte gonad testicle Achilles tendon canal of the cervix ganglionic eminence left ovary right ovary granulocyte right lobe of liver Top expressed in saccule otic vesicle lacrimal gland liver right kidney Ileal epithelium islet of Langerhans granulocyte proximal tubule brown adipose tissue More reference expression data BioGPS n/a
Gene ontology Molecular function transferase activity kinase binding protein serine/threonine kinase activator activity protein binding glycosyltransferase activity NAD+ ADP-ribosyltransferase activity protein ADP-ribosylase activity Cellular component integral component of membrane nuclear envelope endoplasmic reticulum endoplasmic reticulum membrane membrane endoplasmic reticulum tubular network cytosol Biological process endoplasmic reticulum unfolded protein response protein auto-ADP-ribosylation response to unfolded protein protein ADP-ribosylation negative regulation of cell death positive regulation of protein serine/threonine kinase activity NAD biosynthesis via nicotinamide riboside salvage pathway cellular response to leukemia inhibitory factor IRE1-mediated unfolded protein response protein mono-ADP-ribosylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 54956 214424 Ensembl ENSG00000138617 ENSMUSG00000032392 UniProt Q8N5Y8 Q7TMM8 RefSeq (mRNA) NM_017851 NM_001316943 NM_001316944 NM_177460 RefSeq (protein) NP_001303872 NP_001303873 NP_060321 NP_803411 Location (UCSC) Chr 15: 65.23 – 65.3 Mb Chr 9: 65.1 – 65.15 Mb PubMed search [3] [4]
Wikidata
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