PARVB

Beta-parvin is a protein that in humans is encoded by the PARVB gene.^[5][6][7]

PARVB
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4EDL, 4EDM, 4EDN
Identifiers
Aliases	PARVB, CGI-56, parvin beta
External IDs	OMIM: 608121; MGI: 2153063; HomoloGene: 8342; GeneCards: PARVB; OMA:PARVB - orthologs
Gene location (Human) Chr. Chromosome 22 (human)[1] Band 22q13.31 Start 43,999,211 bp[1] End 44,172,939 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 E2 Start 84,116,244 bp[2] End 84,199,889 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in muscle of thigh gastrocnemius muscle apex of heart monocyte left ventricle right auricle of heart islet of Langerhans right lung right adrenal gland upper lobe of left lung Top expressed in blood lumbar spinal ganglion muscle of thigh molar right lobe of liver extraocular muscle soleus muscle digastric muscle atrium yolk sac More reference expression data BioGPS More reference expression data
Gene ontology Molecular function actin binding protein binding Cellular component cytoplasm cytosol cell junction plasma membrane cell projection sarcomere Z discdkac cytoskeleton membrane focal adhesion lamellipodium actin cytoskeleton Biological process actin cytoskeleton reorganization cell adhesion cell projection assembly lamellipodium assembly establishment or maintenance of cell polarity regulating cell shape establishment or maintenance of cell polarity substrate adhesion-dependent cell spreading Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 29780 170736 Ensembl ENSG00000188677 ENSMUSG00000022438 UniProt Q9HBI1 Q9ES46 RefSeq (mRNA) NM_001003828 NM_001243385 NM_001243386 NM_013327 NM_133167 RefSeq (protein) NP_001003828 NP_001230314 NP_001230315 NP_037459 NP_573395 Location (UCSC) Chr 22: 44 – 44.17 Mb Chr 15: 84.12 – 84.2 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Members of the parvin family, including PARVB, PARVA and PARVG, are actin-binding proteins associated with focal contacts.[supplied by OMIM]^[7]