PASD1

PAS domain-containing protein 1 is a protein that in humans is encoded by the PASD1 gene.^[3][4][5]

PASD1
Identifiers
Aliases	PASD1, CT63, OXTES1, PAS domain containing 1, PAS domain containing repressor 1, CT64
External IDs	OMIM: 300993; HomoloGene: 131196; GeneCards: PASD1; OMA:PASD1 - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xq28 Start 151,563,675 bp[1] End 151,676,739 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle right testis left testis gonad human musculoskeletal system muscular system muscle skeletal muscle lower limb muscles muscle of leg n/a More reference expression data BioGPS n/a
Gene ontology Molecular function transcription coactivator binding Cellular component Cry-Per complex nucleus nuclear speck Biological process negative regulation of circadian rhythm negative regulation of transcription, DNA-templated rhythmic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 139135 n/a Ensembl ENSG00000166049 n/a UniProt Q8IV76 n/a RefSeq (mRNA) NM_173493 n/a RefSeq (protein) NP_775764 n/a Location (UCSC) Chr X: 151.56 – 151.68 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

PASD1 has been shown to inhibit the transcriptional activity between CLOCK and BMAL1 which appears to be co-opted in cancer cells to attenuate clock function.^[6][7]