PCDH20

Protocadherin-20 is a protein that in humans is encoded by the PCDH20 gene.^[5]

PCDH20
Identifiers
Aliases	PCDH20, PCDH13, protocadherin 20
External IDs	OMIM: 614449; MGI: 2443376; HomoloGene: 11277; GeneCards: PCDH20; OMA:PCDH20 - orthologs
Gene location (Human) Chr. Chromosome 13 (human)[1] Band 13q21.2 Start 61,409,685 bp[1] End 61,415,522 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14|14 E1 Start 88,702,179 bp[2] End 88,708,832 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in superior frontal gyrus testicle prefrontal cortex hippocampus proper popliteal artery tibial arteries Achilles tendon Brodmann area 9 anterior cingulate cortex Descending thoracic aorta Top expressed in utricle vestibular sensory epithelium vestibular membrane of cochlear duct dentate gyrus dentate gyrus of hippocampal formation granule cell hippocampus proper lumbar subsegment of spinal cord endolymphatic duct Region I of hippocampus proper mammillary body More reference expression data BioGPS More reference expression data
Gene ontology Molecular function calcium ion binding RNA binding Cellular component integral component of membrane plasma membrane membrane integral component of plasma membrane Biological process cell adhesion homophilic cell adhesion via plasma membrane adhesion molecules Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 64881 219257 Ensembl ENSG00000280165 ENSMUSG00000050505 UniProt Q8N6Y1 Q8BIZ0 RefSeq (mRNA) NM_022843 NM_178685 RefSeq (protein) NP_073754 NP_848800 Location (UCSC) Chr 13: 61.41 – 61.42 Mb Chr 14: 88.7 – 88.71 Mb PubMed search [3] [4]
Wikidata
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This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This gene encodes a protein which contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. Although its specific function is undetermined, the cadherin-related neuronal receptor is thought to play a role in the establishment and function of specific cell-cell connections in the brain.^[5]