PD-128,907

PD-128,907 is a drug used in scientific research which acts as a potent and selective agonist for the dopamine D₂ and D₃ receptors.^[1] It is used for studying the role of these receptors in the brain, in roles such as inhibitory autoreceptors that act to limit further dopamine release,^[2] as well as release of other neurotransmitters.^[3] In animal studies, it has been shown to reduce toxicity from cocaine overdose.^[4][5]

PD-128,907

Identifiers
IUPAC name (4aR,10bR)-3,4a,4,10b-Tetrahydro-4-propyl-2H,5H-[1]benzopyrano-[4,3-b]-1,4-oxazin-9-ol
CAS Number	123594-64-9 Y 300576-59-4 (hydrochloride)
PubChem CID	5311346
ChemSpider	23180492 N
ChEMBL	ChEMBL94015 N
CompTox Dashboard (EPA)	DTXSID301018037
Chemical and physical data
Formula	C14H19NO3
Molar mass	249.310 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCCN1CCO[C@H]2[C@H]1COC3=C2C=C(C=C3)O
InChI InChI=1S/C14H19NO3/c1-2-5-15-9-17-7-12-11-6-10(16)3-4-14(11)18-8-13(12)15/h3-4,6,12-13,16H,2,5,7-9H2,1H3/t12-,13-/m1/s1 N Key:ZFSOBPVEIKTNQS-CHWSQXEVSA-N N
NY (what is this?)  (verify)

See also

• 7-OH-DPAT
• PF-219,061
• PF-592,379