PF-592,379

PF-592,379
Clinical data
Routes of; administration	Oral
Legal status
Legal status	Investigational (discontinued);
Identifiers
	IUPAC name 5-[(2R,5S)-5-methyl-4-propylmorpholin-2-yl]pyridin-2-amine;
CAS Number	710655-15-5 ;
PubChem CID	10263487;
IUPHAR/BPS	7683;
ChemSpider	8438966;
UNII	66B7UY5K7I;
CompTox Dashboard (EPA)	DTXSID901030407 ;
Chemical and physical data
Formula	C13H21N3O
Molar mass	235.331 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCCN([C@@H](C)CO1)C[C@H]1C2=CN=C(N)C=C2;
	InChI InChI=1S/C13H21N3O/c1-3-6-16-8-12(17-9-10(16)2)11-4-5-13(14)15-7-11/h4-5,7,10,12H,3,6,8-9H2,1-2H3,(H2,14,15)/t10-,12-/m0/s1; Key:DFTCYTDJDXZFSK-JQWIXIFHSA-N;

PF-592,379 is a drug developed by Pfizer which acts as a potent, selective and orally active agonist for the dopamine D₃ receptor, which was under development as a potential medication for the treatment of female sexual dysfunction and male erectile dysfunction. Unlike some other less selective D₃ agonists, a research study showed that PF-592,379 has little abuse potential in animal studies, and so was selected for further development and potentially human clinical trials.^[1]^[2] Development has since been discontinued.^[3]

Quick facts Clinical data, Routes ofadministration ...

[1]

[2]

[3]

PF-592,379

See also

References

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